Other terms
Familial Periodic Paralyses,Periodic Paralyses, Familial,Familial Periodic Paralysis,Periodic Paralysis, Familial,Paralysis, Familial Periodic,Normokalemic Periodic Paralysis,Normokalemic Periodic Paralyses,Paralyses, Normokalemic Periodic,Paralysis, Normokalemic Periodic,Periodic Paralyses, Normokalemic,Periodic Paralysis, Normokalemic
Description
Paralyses, Familial Periodic: A heterogenous group of inherited disorders characterized by recurring attacks of rapidly progressive flaccid paralysis or myotonia. These conditions have in common a mutation of the gene encoding the alpha subunit of the sodium channel in skeletal muscle. They are frequently associated with fluctuations in serum potassium levels. Periodic paralysis may also occur as a non-familial process secondary to THYROTOXICOSIS and other conditions. (From Adams et al., Principles of Neurology, 6th ed, p1481)
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