Other terms
Creutzfeldt Jakob Syndrome,Syndrome, Creutzfeldt-Jakob,Creutzfeldt Jacob Disease,Disease, Creutzfeldt Jacob,Jacob Disease, Creutzfeldt,Creutzfeldt-Jakob Disease,Creutzfeldt Jakob Disease,Disease, Creutzfeldt-Jakob,Jakob-Creutzfeldt Syndrome,Jakob Creutzfeldt Syndrome,Syndrome, Jakob-Creutzfeldt,Spongiform Encephalopathy, Subacute,Encephalopathies, Subacute Spongiform,Encephalopathy, Subacute Spongiform,Spongiform Encephalopathies, Subacute,Subacute Spongiform Encephalopathies,Subacute Spongiform Encephalopathy,CJD (Creutzfeldt-Jakob Disease),CJD (Creutzfeldt Jakob Disease),Jakob-Creutzfeldt Disease,Disease, Jakob-Creutzfeldt,Jakob Creutzfeldt Disease,Creutzfeldt-Jakob Disease, Familial,Creutzfeldt Jakob Disease, Familial,Creutzfeldt-Jakob Diseases, Familial,Disease, Familial Creutzfeldt-Jakob,Familial Creutzfeldt-Jakob Diseases,Familial Creutzfeldt-Jakob Disease,Familial Creutzfeldt Jakob Disease,New Variant Creutzfeldt-Jakob Disease,New Variant Creutzfeldt Jakob Disease,V-CJD (Variant-Creutzfeldt-Jakob Disease),Variant Creutzfeldt-Jakob Disease,Creutzfeldt-Jakob Disease, Variant,Variant Creutzfeldt Jakob Disease,Creutzfeldt-Jakob Disease, New Variant,Creutzfeldt Jakob Disease, New Variant
Description
Creutzfeldt-Jakob Syndrome: A rare transmissible encephalopathy most prevalent between the ages of 50 and 70 years. Affected individuals may present with sleep disturbances, personality changes, ATAXIA; APHASIA, visual loss, weakness, muscle atrophy, MYOCLONUS, progressive dementia, and death within one year of disease onset. A familial form exhibiting autosomal dominant inheritance and a new variant CJD (potentially associated with ENCEPHALOPATHY, BOVINE SPONGIFORM) have been described. Pathological features include prominent cerebellar and cerebral cortical spongiform degeneration and the presence of PRIONS. (From N Engl J Med, 1998 Dec 31;339(27))
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