Other terms
Pontine Myelinolysis, Central,Myelinoclasis, Central Pontine,Central Pontine Myelinoclasis,Central Pontine Myelinolysis,Extrapontine Myelinolysis,Extrapontine Myelinolyses,Myelinolyses, Extrapontine,Myelinolysis, Extrapontine,Extrapontine Myelinoclasis,Extrapontine Myelinoclases,Myelinoclases, Extrapontine,Myelinoclasis, Extrapontine
Description
Myelinolysis, Central Pontine: A demyelinating condition affecting the PONS and characterized clinically by an acute progressive QUADRIPLEGIA; DYSARTHRIA; DYSPHAGIA; and alterations of consciousness. Pathologic features include prominent demyelination in the central PONS with sparing of axons and neurons. This condition is usually associated with systemic disorders such as HYPONATREMIA; chronic ALCOHOLISM; LIVER FAILURE; severe BURNS; malignant NEOPLASMS; hemorrhagic PANCREATITIS; HEMODIALYSIS; and SEPSIS. The rapid medical correction of hyponatremia has been cited as a cause of this condition. (From Adams et al., Principles of Neurology, 6th ed, pp1125-6)
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