Other terms
Olivopontocerebellar Atrophy,Atrophy, Olivopontocerebellar,Olivo-Ponto-Cerebellar Atrophy,Atrophy, Olivo-Ponto-Cerebellar,Olivo Ponto Cerebellar Atrophy,Dejerine-Thomas Syndrome,Dejerine Thomas Syndrome,Syndrome, Dejerine-Thomas,Presenile Ataxia,Ataxia, Presenile,Ataxias, Presenile,Presenile Ataxias,Pontoolivocerebellar Atrophy,Atrophy, Pontoolivocerebellar,Pontoolivocerebellar Atrophies,Olivopontocerebellar Degeneration,Degeneration, Olivopontocerebellar,Degenerations, Olivopontocerebellar,Olivopontocerebellar Degenerations,Olivo-Ponto-Cerebellar Degeneration,Degeneration, Olivo-Ponto-Cerebellar,Degenerations, Olivo-Ponto-Cerebellar,Olivo Ponto Cerebellar Degeneration,Olivo-Ponto-Cerebellar Degenerations,Nonfamilial Olivopontocerebellar Atrophy,Atrophy, Nonfamilial Olivopontocerebellar,Nonfamilial Olivopontocerebellar Atrophies,Olivopontocerebellar Atrophies, Nonfamilial,Olivopontocerebellar Atrophy, Nonfamilial,Olivopontocerebellar Atrophy, Idiopathic,Atrophy, Idiopathic Olivopontocerebellar,Idiopathic Olivopontocerebellar Atrophies,Idiopathic Olivopontocerebellar Atrophy,Olivopontocerebellar Atrophies, Idiopathic,Familial Olivopontocerebellar Atrophy,Atrophy, Familial Olivopontocerebellar,Familial Olivopontocerebellar Atrophies,Olivopontocerebellar Atrophies, Familial,Olivopontocerebellar Atrophy, Familial,Inherited Olivopontocerebellar Atrophy,Atrophy, Inherited Olivopontocerebellar,Inherited Olivopontocerebellar Atrophies,Olivopontocerebellar Atrophies, Inherited,Olivopontocerebellar Atrophy, Inherited
Description
Olivopontocerebellar Atrophies: A group of inherited and sporadic disorders which share progressive ataxia in combination with atrophy of the CEREBELLUM; PONS; and inferior olivary nuclei. Additional clinical features may include MUSCLE RIGIDITY; NYSTAGMUS, PATHOLOGIC; RETINAL DEGENERATION; MUSCLE SPASTICITY; DEMENTIA; URINARY INCONTINENCE; and OPHTHALMOPLEGIA. The familial form has an earlier onset (second decade) and may feature spinal cord atrophy. The sporadic form tends to present in the fifth or sixth decade, and is considered a clinical subtype of MULTIPLE SYSTEM ATROPHY. (From Adams et al., Principles of Neurology, 6th ed, p1085)
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