Other terms
fms Oncogene Protein gp140,v-fms Protein,v fms Protein,gp140(v-fms),fms Oncogene Product gp140,gp140 v-fms,gp140 v fms,v-fms, gp140,fms Oncogene Protein gp120,gp120(v-fms),gp120 v-fms,gp120 v fms,v-fms, gp120,fms Oncogene Product gp120
Description
Oncogene Protein gp140(v-fms): Transforming glycoprotein coded by the fms oncogene from the Susan McDonough strain of feline sarcoma virus (SM-FeSV). The oncogene protein v-fms lacks sequences, which, in the highly homologous proto-oncogene protein c-fms (CSF-1 receptor), normally serve to regulate its tyrosine kinase activity. The missing sequences in v-fms mimic the effect of ligand and lead to constitutive cell growth. The protein gp120(v-fms) is post-translationally modified to generate gp140(v-fms).
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